Projects

General Director
RNDr. Mojmír Mach, PhD.

International

Finished
  • Molecular logic lab-on-a-vesicle for intracellular diagnostics
    Program: Horizon 2020
    Duration: 1. 11. 2018 – 31. 10. 2023

National

Current
  • Experimental real-life risk simulation approach: The effect of long-term exposure to a chemical mixture of pesticides, contaminants and food additives at low doses in extended one-generation reproductive toxicity study
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Molecular mechanisms implicated in corticosteroid-monoamine interaction in stress-related cardio- and neuropathologies
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • In vitro biocompatibility testing of medical devices (MDs) and new generation bio-materials for MDs
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
Finished
  • Bio-compatibility assessment of medical devices and novel medical device materials using in vitro methods based on 3D reconstructed human tissue models.
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2023
  • Prenatal programming of adult diseases: treatment and prevention of outcomes of gestational hypoxia in rat offspring
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2023
  • Development of products by modification of natural compounds and study of their multi-modal effects onCOVID-19 disease
    Program:
    Duration: 1. 7. 2021 – 30. 6. 2023
  • Investigation of anatomical-functional differences between the effects of aripiprazole and quetiapine, atypical antipsychotics with similar therapeutic indications, but different impact on brain dopaminergic receptors, in experimental animals
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2020
  • Prenatal programming of psychiatric diseases: experimental approaches for evaluation of causes and mechanisms of their origin
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2019
  • Mechanisms, early detection and therapy of asphyxial injury in perinatal period - comparison of experimental data with clinical observation of asphyxial newborns
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
  • Study of consequences of maternal depression and antidepressant venlafaxine treatment on functional development of the brain and behavior of rat offspring
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
  • Prenatal programming of psychiatric diseases: experimental approaches for evaluation of causes and mechanisms of their origin
    Program: VEGA
    Duration: 1. 1. 2012 – 31. 12. 2015
  • The study of mechanisms and possible early detection of embryofetal damage caused by intrauterine perinatal hypoxia
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 10. 2014
  • Early screening of anxiolytic and antidepressive properties of pyridoindole derivatives
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Experimental models of perinatal asphyxia in evaluation of behavioral disorders and possibility of pharmacological intervention
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Developmental Origin of Metabolic Syndrome:Hypertension, Diabetes and Dyslipidemia
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Molecular mechanisms of new drugs influencing oxidative stress - important ethiopathogenetic factor of numerous diseases
    Program: SRDA
    Duration: 1. 9. 2006 – 31. 10. 2009
  • Contribution to prevention and treatment of behavioural disorders evoked by hypotic-ischaemic damage of the brain in perinatal period: experimental model of asphyxia and administration of substances with antiradical and antioxidative effects
    Program: VEGA
    Duration: 1. 1. 2005 – 1. 12. 2007