Ladislav Š o l t é s - Curriculum Vitae

 

* PROJECTS *

 

 

Effects of natural and synthetic substances on oxidative damage of biomacromolecules. Pro- and antioxidative mechanisms. VEGA No.: 2/0019/19, principal investigator Valachova K.

 

 

* PUBLICATION   LIST   (Years  20172021) *

 

Publications in PDF (1997–present)

 

PowerPoint presentations

 

2017

Tamer M. T., Hassan M. A., Omer A. M., Valachova K., Mohamed S., Mohy Eldin M. S., Collins M. N., Soltes L. Antibacterial and antioxidative activity of O-amine functionalized chitosan. Carbohydr. Polym. 169 (2017) 441-450

 

Matyasovsky J., Sedliacik J., Valachova K., Novak I., Jurkovic P., Duchovic P., Micusik M., Kleinova A., Soltes L. Antioxidant stability of keratin hydrolysates prepared from leather waste. J. Am. Leather Chem. Assoc. 112 (2017) 327-337

 

2018

Matyasovsky J., Sedliacik J., Jurkovic P., Duchovic P., Soltes L. Modification and application possibilities of biocomposites based on thermoplastic collagen. In.: "Applied Chemistry and Chemical Engineering, Volume 2: Principles, Methodology, and Evaluation Methods" A. K. Haghi, L. Pogliani, D. Balkose, O. V. Mukbaniani, A. G. Mercader (eds), Apple Academic Press, Taylor & Francis Group, New Jersey, USA, (2018) pp. 73-83 ISBN: 9781771885584 Product Info

 

Valachova K., Topolska D., Mendichi R., Rychly J., Soltes L. Protective effects of catalase indicate hydrogen peroxide involvement in hyaluronan degradation initiated by Cu(II) ions plus ascorbate in situ. In.: "Applied Chemistry and Chemical Engineering, Volume 2: Principles, Methodology, and Evaluation Methods" A. K. Haghi, L. Pogliani, D. Balkose, O. V. Mukbaniani, A. G. Mercader (eds), Apple Academic Press, Taylor & Francis Group, New Jersey, USA, (2018) pp. 157-173 ISBN: 9781771885584 Product Info

 

Sedliacik J., Matyasovsky J., Jurkovic P., Smidriakova M., Soltes L. Modification of urea-formaldehyde resin with collagen biopolymers. In.: "Applied Chemistry and Chemical Engineering, Volume 1: Mathematical and Analytical Techniques" A. K. Haghi, D. Balkose, O. V. Mukbaniani, A. G. Mercader (eds), Apple Academic Press, Taylor & Francis Group, New Jersey, USA, pp. 275-297 ISBN: 9781771885157 Product Info

 

Tamer M. T., Valachova K., Omer A. M., Sabet M. M., Soltes L. Effects of glutathione, phosphonate, or sulfonated chitosans and their combination on scavenging free radicals. In.: "High-Performance Materials and Engineered Chemistry" F. Torrens, D. Balkose, S. Thomas (eds), Apple Academic Press, Taylor & Francis Group, New Jersey, USA, (2018) pp. 371-389 ISBN: 9781771885980 Product Info

 

Tamer M. T., Collins M. N., Valachova K., Hassan M. A., Omer A. M., Mohy-Eldin M. S., Svik K., Jurcik R., Ondruska L., Biro C., Albadarin A. B. Soltes L. MitoQ loaded chitosan-hyaluronan composite membranes for wound healing. Materials 11(2018)569 Full-text paper
 

Valachova K., Topolska D., Soltes L. Protective effect of mitochondrially targeted antioxidant MitoQ on oxidatively stressed fibroblasts. Chem. Papers 72(2018)1223-1230 Download

 

Tamer M. T., Valachova K., Hassan M. A., Omer A. M., El-Shafeey M. E. A., Mohy Eldin M. S., Soltes L. Chitosan/hyaluronan/edaravone membranes for anti-inflammatory wound dressing: In vitro and in vivo evaluation studies. Materials Science & Engineering C 90(2018)227-235 Download

 

Soltes L., Tamer M. T., Veverka M., Valachova K., Mohy Eldin M. S. Self-associating biopolymeric membranes as carriers of remedies with antioxidative properties and their usage. Slovak Patent No.:  288581 (2018)

 

Soltes L., Valachova K. Biopolymer hyaluronan messenging the status of synovial joints. Advances in Chemistry Research, Vol. 46, J. C. Taylor (ed), Nova Science Publishers, Inc., New York, 2018 pp. 157-180 ISBN: 9781536142167 Product Info

 

2019

Valachova K., Juranek I., Rapta P., Valent I., Soltes L. On infusion of high-dose ascorbate in treating cancer: Is it time for N-acetylcysteine pretreatment to enhance susceptibility and to lower side effects? Medical Hypotheses 122 (2019) 8-9 Download

 

Valachova K. Topolska D., Nagy M., Juranek I., Soltes L. Antioxidative activity of Azadirachta indica, Ocimum tenuiflorum, and Withania somnifera. In: "Physical Chemistry for Chemists and Chemical Engineers. Multidisciplinary Research Perspectives" A. V. Vakhrushev, R. Haghi, J. V. de Julian-Ortiz (eds), Apple Academic Press, New Jersey, USA, (2019) pp. 75-93 ISBN: 9781771886550 Product Info

 

Valachova K., Tamer M. T., Veverka M., Soltes L. Preparation of two quercetin derivatives and evaluation of their antioxidative activity. Engineering Technology and Industrial Chemistry with Applications, R. Haghi, F. Torrens (eds), Apple Academic Press, Taylor & Francis Group, New Jersey, USA, 2019 pp. 189-208 ISBN: 9781771886376 Product Info

 

Valachova K., Mach M., Dubovicky M., Soltes L. The importance of ergothioneine synthesis in ancient-time by organisms living in oxygen free atmosphere. Medical Hypotheses 123( 2019) 72-73 Download

 

Kura B., Bagchi A., Singal P., Barancik M., LeBaron T., Valachova K., Soltes L., Slezak J. Molecular hydrogen (H2): Potential in mitigating oxidative stress-induced cardiotoxicity. Canadian Journal of Physiology and Pharmacology 97(2019)287-292, doi: 10.1139/cjpp-2018-0604

 

2020

Novak I., Kleinova A., Matyasovsky J., Jurkovic P., Duchovic P., Valachova K., Soltes L. Investigation of Wood Surfaces Modification by Radio-Frequency Plasma. In: "Research Methodologies and Practical Applications of Chemistry" L. Pogliani, A. K. Haghi, N. Islam (eds), Apple Academic Press, New Jersey, USA 2020 pp. 269-280 ISBN: 9781771887847 Product Info

 

Valachova K., Svik K., Biro Cs., Soltes L. Skin wound healing with composite biomembranes loaded by tiopronin or captopril. J. Biotechnol. 310(2020)49-53 https://doi.org/10.1016/j.jbiotec.2020.02.001

 

Tamer M. T., Hassan M. A., Valachova K., Omer A. M., El-Shafeey M. E. A., Mohy Eldin M. S., Soltes L. Enhancement of wound healing by chitosan/hyaluronan polyelectrolyte membrane loaded with glutathione: in vitro and in vivo evaluations. J. Biotechnol. 310 (2020) 103-113 https://doi.org/10.1016/j.jbiotec.2020.02.002

 

Valachova K., Hafez E. E., Nagy M., Soltes L. Antioxidative properties of Punica granatum, Peganum harmala, Dianthus caryophyllus, and Vitis vinifera extracts against free radicals. In: "Green Chemistry and Biodiversity, Principles, Techniques, and Correlations" C. N. Aguilar, S. C. Ameta, A. K. Haghi (eds), Apple Academic Press, New Jersey, USA 2020 pp. 135-152 ISBN: 9781771887946 Product Info

 

Soltes L., Valachova K., Mach M., Juranek I..Composite membranes containing a smart-released cytoprotectant targeting the inflamed tissue and use thereof. European Patent Application EP20020280.2 (priority date 17/06/2020)

 

Valachova K., Mach M., Soltes L. Oxidative degradtion of high-molar-mass hyaluronan: Effects of some indole derivatives to hyaluronan decay. Int. J. Mol. Sci. 20 (2020) art. no. 5609

 

Maronek M., Novak I., Michalec I., Matyasovsky J., Jurkovic P., Valachova K., Soltes L. Analysis of fumes arising during fabrication of hybrid adhesive-laser joints. In: "Chemistry and Chemical Engineering for Sustainable Development. Best Practices and Research Directions" M. A. Esteso, A. C. F. Ribeiro, A. K. Haghi (eds), Apple Acedemic Press, New Jersey, USA (November 2020) pp. XX-YY ISBN: 9781771888707 Product Info

 

Hassan M. A., Tamer M. T., Valachova K., Omer A. M., El-Shafeey M., Mohy Eldin M. S., Soltes L. Fabrication of chitosan/hyaluronan membranes loaded with quercetin as an efficient antioxidant polyelectrolyte wound dressing: In vitro and in vivo evaluation.(2020) in preparation

 

Valachova K., Svík K., Jurcik R., Ondruska L., Soltes L. Ergothioneine as effective antioxidant in vitro and in vivo., in preparation

 

Valachova K., Soltes L. Review on hyaluronan. (2020) in preparation

 

Valachova K., Soltes L. Effects of ergothioneine in wound healing. (2020) in preparation

 

Valachova K., Rapta P., Soltes L. Effects of redox-active manganese(III)-porphynoid compounds on high-molar-mass hyaluronan degradation induced by ascorbate and cupric ions. (2020) in preparation

 

Valachova K., Soltes L. Neves M. ... manganese complexes. (2020) in preparation

 

Valachova K., Soltes L. Effects of aldose reductase inhibitors on oxidatively damaged hyaluronan., in preparation

 

2021

Valachova K., Susanikova I., Topolska D., Bogi E., Soltes L. Effects of N-acetylcysteine, glutathione, and glutathione disulfide on NIH 3T3, VH10 and MCF-7 cells exposed to ascorbate and Cu(II) ions. In: "Green Chemistry and Sustainable Technology Biological, Pharmaceutical, and Macromolecular Systems" S. A. Dake, R. S. Shinde, S. C. Ameta, A. K. Haghi (eds), Apple Academic Press, Palm Bay, Florida, USA (2021) pp. 77-93 ISBN: 9781771888622 Product Info

 

Valachova K., Rapta P., Soltes L. Manganese porphyrins as pro-oxidants in high-molar-mass hyaluronan oxidative degradation. In: "Green Chemistry and Green Engineering. Processing, Technologies, Properties, and Applications" S. Kulkarni, N. K. Rawat, A. K. Haghi (eds), Apple Acedemic Press, New Jersey, USA (February 2021) pp. XX-YY ISBN: 9781771889001 Product Info

 

 

 

* CURRICULUM   VITAE *

 

 

Education, Earned Degree

 

1968-73               Faculty of Chemical Technology, Slovak Technical University, Bratislava, Dipl. Ing. - 1973 macromolecular chemistry (Diploma Work/MS-Thesis: Investigation of interactions in ternary polymeric systems by GPC, pp. 52. Research adviser: Dr. Dusan Berek)

 

1973-77               Faculty of Chemical Technology, Slovak Technical University, Bratislava, PhD. - 1978 macromolecular chemistry (PhD Thesis: Polymolecularity of high molecular mass polystyrene prepared by heterogeneously initiated radical polymerization, pp. 119. Research adviser: Prof. Dr. Darina Mikulasova)

 

1993                    DSc. - analytical chemistry (Research Prof. Thesis: Liquid chromatographic separation  methods for the analysis of biological materials, pp. 128.)

 

Email:                  ladislav.soltes@savba.sk                            

         

                                      Who is L. Soltes (in slovak)

 

Research Training/Experience

 

since 1979            Bioanalytically Applied Liquid Chromatographic Separation Methods

since 2012            Laboratory of Bioorganic Chemistry of Drugs

 

HPLC methods for the determination of xenobiotics in body fluids.

HPLC and HPTLC methods for isolation, purification, and evidence of drug metabolites.

HPLC methods for the study of drug binding to proteins.

SEC (GPC)   methods for the determination of molar mass and the distribution of molar masses of polymers, both natural and synthetic.

 

Current Research Interests and Achievements

 

Development of rotational viscometric methods to characterize antioxidative and/or free-radical-scavenging properties of prospective drugs.

 

Publications/Citations

 

Author/co-author of      > 150  Scientific Papers (ranked: Current Contents)

                                    > 2700 Citations (ranked: Scientific Citation Index)

 

Memberships

 

ISHAS - International Society for Hyaluronan Sciences

 

Academic Honor

 

1990 & 2000        Award of the Slovak Academy of Sciences, Bratislava, Slovakia

 

2008                     Scientist of the year 2007, Slovakia
 

Status                  Married (with Nelly), two sons (Thomas 1974, George 1977)

 

Languages              Slovak, Czech, English, French, Hungarian, Russian