SDS Award for our Scientists

Ing. Marta Šoltésová Prnová, PhD., Ing. Milan Štefek, PhD and co-authors from Dept. of  Biochemical Pharmacology received Slovak Diabetologic Society Award for their experimental research new selective aldosareductase inhibitors.
  • Stefek, M. Soltesova Prnova, M. Majekova, C. Rechlin, A. Heine, G.  Klebe, Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold. J. Med. Chem., 2015, vol. 58, pp. 2649-2657. (2014 IF: 5.447)
  • Soltesova Prnova, J.Ballekova, A. Gajdosikova, A. Gajdosik, M. Stefek, A novel carboxymethylated mercaptotriazinoindole inhibitor of aldose reductase interferes with the polyol pathway in streptozotocin-induced diabetic rats. Physiol. Res. 2015, vol. 64, pp. 587-591. (2014 IF: 1.293)
  • Soltesova Prnova, J. Ballekova, M. Majekova, M. Stefek, Antioxidant action of 3-mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid, an efficient aldose reductase inhibitor, in a 1,1′-diphenyl-2-picrylhydrazyl assay and in the cellular system of isolated erythrocytes exposed to tert-butyl hydroperoxide. Redox Rep. 2015 vol. 20, pp. 282-288. (2014 IF: 1.522)
  • Stefek, I. Milackova, B. Diez-Dacal, D. Perez-Sala, M. Soltesova Prnova, Use of 5-carboxymethyl-3-mercapto-1,2,4-triazino-[5,6-b]- indoles and their pharmaceutical composition.Patent WO 2015/057175 A1, 2015.

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